Table 3

Comparison of α and statistical power for iterated false positive rate and variable variance. The values are the same as those given in Table 1 and Table 2 except the variance for each sample was drawn from a uniform distribution between 0.05 and 1 during the simulation. The significance level (α) for the PE method was iterated so that the observed false positive rate matched that of the MP method where α was held constant.
n1 = n2 = n
 ν0
 αPE
 αMP
 FPPE
 FPMP
 PowerPE
 PowerMP
2
 0
 -
 0.05
 -
 0.0554
 -
 0.4038
2
 2
 0.190
 0.05
 0.0593
 0.0592
 0.5876
 0.5756
2
 6
 0.090
 0.05
 0.0522
 0.0521
 0.6838
 0.6859
2
 16
 0.067
 0.05
 0.0573
 0.0571
 0.7563
 0.7566

Fox and Dimmic BMC Bioinformatics 2006 7:126   doi:10.1186/1471-2105-7-126