Open Access Software

HDBStat!: A platform-independent software suite for statistical analysis of high dimensional biology data

Prinal Trivedi1, Jode W Edwards1,3, Jelai Wang1, Gary L Gadbury1,2, Vinodh Srinivasasainagendra1, Stanislav O Zakharkin1, Kyoungmi Kim1, Tapan Mehta1, Jacob PL Brand1,4, Amit Patki1, Grier P Page1 and David B Allison1*

Author Affiliations

1 Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA

2 Department of Mathematics and Statistics, University of Missouri-Rolla, Rolla, MO 65409, USA

3 Department of Agronomy, Iowa State University, Ames, IA 50011, USA

4 Pennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA

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BMC Bioinformatics 2005, 6:86 doi:10.1186/1471-2105-6-86

Published: 6 April 2005

Abstract

Background

Many efforts in microarray data analysis are focused on providing tools and methods for the qualitative analysis of microarray data. HDBStat! (High-Dimensional Biology-Statistics) is a software package designed for analysis of high dimensional biology data such as microarray data. It was initially developed for the analysis of microarray gene expression data, but it can also be used for some applications in proteomics and other aspects of genomics. HDBStat! provides statisticians and biologists a flexible and easy-to-use interface to analyze complex microarray data using a variety of methods for data preprocessing, quality control analysis and hypothesis testing.

Results

Results generated from data preprocessing methods, quality control analysis and hypothesis testing methods are output in the form of Excel CSV tables, graphs and an Html report summarizing data analysis.

Conclusion

HDBStat! is a platform-independent software that is freely available to academic institutions and non-profit organizations. It can be downloaded from our website http://www.soph.uab.edu/ssg_content.asp?id=1164 webcite.