BMC Bioinformatics

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Open Access Highly Access Research article

Structural comparison of metabolic networks in selected single cell organisms

Dongxiao Zhu1,3 and Zhaohui S Qin2*

Author Affiliations

1 Bioinformatics Program, University of Michigan, Ann Arbor, MI 48109, USA

2 Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA

3 Department of Statistics, University of Michigan, Ann Arbor, MI 48109, USA

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BMC Bioinformatics 2005, 6:8 doi:10.1186/1471-2105-6-8

Published: 14 January 2005

Additional files

Additional File 1:

Four-node motifs found in the metabolic networks in different species. The number of connecting nodes for each network is shown. For each motif, the numbers of appearances in real networks (Nreal) and in randomized networks (Nrand ± SD, all values rounded) are shown. The p-values of all motifs are less than 0.01, as determined by comparing to 1000 randomized networks. Each motif occurs at least four times in one network. Other restrictions apply. Motifs were detected and generated using program found in Milo et al. [15] and the motif dictionary therein.

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