Influence on expression values. a) Expression values for four chips of subject 2, original data vs. filtered data. b) T-statistics for the comparison of activated vs. activated in the presence of the repressor; raw vs. filtered data. Open circles: p < 0.01 with the original data only, solid black dots: p < 0.01 with the filtered set only; large grey solid dots: p < 0.01 with both sets.
Suárez-Fariñas et al. BMC Bioinformatics 2005 6:65 doi:10.1186/1471-2105-6-65