Algorithm to detect compact defects. Outliers (B) are declared based on the distribution function of the E (A). Then, clusters of outliers are identified with a FloodFill algorithm (C), and a size threshold is applied to eliminate clusters made of single or only a few pixels (D).
Suárez-Fariñas et al. BMC Bioinformatics 2005 6:294 doi:10.1186/1471-2105-6-294