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An example of protein location prediction. The host YGL115W has four guest proteins that share four statistically significant signatures. The host and all its guests with known location were found in cytoplasm. Thus the location of YGL208W was predicted as cytoplasm. The prediction was then confirmed with the ontology annotation in SGD database. The p-value of the occurrence is the probability that a single random subsequence of the length of the motif matches the motif. |
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| Guest |
Motif ID |
P-value |
Guest location |
|
|
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| YER027C |
YGL115W_1 |
3.17E-76 |
cytoplasm |
| YGL208W |
YGL115W_1 |
7.48E-75 |
|
| YDR422C |
YGL115W_1 |
4.78E-48 |
cytoplasm |
| YER027C |
YGL115W_2 |
3.87E-56 |
cytoplasm |
| YGL208W |
YGL115W_2 |
8.48E-57 |
|
| YDR422C |
YGL115W_2 |
3.64E-37 |
cytoplasm |
| YER027C |
YGL115W_3 |
6.83E-77 |
cytoplasm |
| YGL208W |
YGL115W_3 |
6.37E-71 |
|
| YDR028C |
YGL115W_3 |
9.81E-38 |
cytoplasm |
| YER027C |
YGL115W_4 |
5.62E-22 |
cytoplasm |
| YGL208W |
YGL115W_4 |
7.23E-24 |
|
| YDR477W |
YGL115W_4 |
1.89E-14 |
cytoplasm |
Fang et al. BMC Bioinformatics 2005 6:277 doi:10.1186/1471-2105-6-277 |
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