BMC Bioinformatics

official impact factor 3.03

Open Access Methodology article

A stepwise framework for the normalization of array CGH data

Mehrnoush Khojasteh1,2*, Wan L Lam1, Rabab K Ward2 and Calum MacAulay1

Author Affiliations

1 British Columbia Cancer Research Centre, Vancouver, BC, Canada

2 Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada

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BMC Bioinformatics 2005, 6:274 doi:10.1186/1471-2105-6-274

Published: 18 November 2005

Additional files

Additional File 1:

Supplemental table 1. A description of array CGH experiments that simulate varying degrees of normal diploid cells contamination in a population of cancer cells carrying a single copy alteration. A more detailed description can be found in [5].

Additional file 2 - Supplemental table 2

Format: DOC Size: 39KB Download file

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Additional File 2:

Supplemental table 2. A Description of array CGH experiments involving hybridization of genomic DNAs from cell lines containing varying numbers of X chromosomes that simulate varying levels of gene amplification and deletion for each of the X-chromosomal genes present on the cDNA array. A more detailed description can be found in http://smd.stanford.edu webcite.

Additional file 2 - Supplemental table 2

Format: DOC Size: 30KB Download file

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Open Data