Table 1

System performance measures. Performance was measured based on the program's ability to correctly discriminate CTT proteins from non-CTT proteins. MCC = Mathews' Correlation Coefficient [1].

Program

TP

FP

TN

FN

Sensitivity

Specificity

MCC

TargetP

55

8

307

2

96%

87%

90%

SignalP3 NN – Cmax

52

48

267

5

91%

52%

62%

SignalP3 NN – Ymax

55

9

306

2

96%

86%

89%

SignalP3 NN – Smax

56

9

306

1

98%

86%

90%

SignalP3 NN – Smean

55

17

298

2

96%

76%

83%

SignalP3 NN – D

55

7

308

2

96%

89%

91%

SignalP3 HMM Cmax

46

9

306

11

81%

84%

79%

SignalP3 HMM Sprob

56

17

298

1

98%

77%

84%

SignalP2 NN – Ymax

56

14

301

1

98%

80%

86%

SignalP2 NN – Cmax

54

28

287

3

95%

66%

75%

SignalP2 NN – Smean

57

13

302

0

100%

81%

88%

SignalP2 NN – Smax

56

21

294

1

98%

73%

81%

SignalP2 HMM Sprob

57

21

294

0

100%

73%

83%

SignalP2 HMM Cmax

36

3

312

21

63%

92%

73%

Phobius

55

13

302

2

96%

81%

86%

PrediSi

52

12

303

5

91%

81%

83%

ProtComp NN

46

32

283

11

81%

59%

62%

Klee and Ellis BMC Bioinformatics 2005 6:256   doi:10.1186/1471-2105-6-256