Table 4

Differences found between AutoFACT and PEDANT annotations for Saccharomyces cerevisiae

ID
PEDANT Annotation
AutoFACT Annotation
AutoFACT Score
AutoFACT E-value
AutoFACT % Identity

yal048c
vacuolar aspartic protease
GON1; possible rho-like GTPase involved in secretory vesicle transport
1724
0.0
50% (360/718)
yhr064c
SSZ1 – regulator protein involved in pleiotropic drug resistance
multi-domain protein
651
3.00E-68
28% (154/539)
yhr046c
INM1 – inositol-1(or 4)-monophosphatase
*Protein qutG related cluster
378
4.00E-35
31% (99/310)
yhr143w
DSE2 – glucan 1,3-beta-glucosidase activity
multi-domain protein
229
2.00E-19
25% (70/278)
yhl043w
ECM34 – involved in cell wall biogenesis and architecture
DUP domain-containing protein
205
5.00E-17
36% (26/72)
yal047c
SPC72 – Stu2p Interactant
*Repeat organellar protein related cluster
160
2.00E-09
20% (124/620)
yhr167w
THP2 – subunit of the THO complex, which appears to functionally connect transcription elongation with mitotic recombination
*Myosin heavy chain related cluster
129
2.00E-06
24% (51/210)
yhr154w
RTT107 – Establishes Silent Chromatin
BRCT domain-containing protein
118
4.00E-06
28% (24/83)
yhl020c
OPI1 – negative regulator of phospholipid biosynthesis pathway
multi-domain protein
114
5.00E-06
24% (30/123)
yhr196w
UTP9 – U3 snoRNP protein
Borrelia_orfA domain-containing protein
104
1.00E-04
19% (75/376)

Annotations in bold are the same as the original annotations found in the Saccharomyces Genome Database. AutoFACT annotations marked with an asterisk (*) are considered false positives.

Koski et al. BMC Bioinformatics 2005 6:151   doi:10.1186/1471-2105-6-151