|
Distribution of poly (dA.dT) repeats of various lengths in the 5' upstream regions of housekeeping and tissue specific genes. |
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| Poly (dA.dT) stretch (bp) |
No. of repeat stretches in the two classes |
No. of genes with repeats in 5' region (%) |
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|
|
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| Hkg# |
Tsg* |
Hkg# |
Tsg* |
§P-value |
|
|
|
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| >10 |
443 |
345 |
268 (51.0) |
240 (43.0) |
1.31E-04 |
| >11 |
381 |
297 |
243 (46.3) |
214 (38.4) |
3.25E-04 |
| >12 |
339 |
248 |
226 (43.1) |
184 (33.0) |
6.10E-05 |
| >13 |
295 |
207 |
209 (39.8) |
156 (28.0) |
4.29E-05 |
| >14 |
251 |
168 |
188 (35.8) |
128 (22.9) |
2.77E-05 |
| >15 |
209 |
140 |
164 (31.2) |
111 (19.9) |
8.83E-05 |
| >16 |
180 |
116 |
146 (27.8) |
99 (17.7) |
7.58E-05 |
| >17 |
155 |
103 |
134 (25.5) |
88 (15.8) |
2.42E-04 |
| >18 |
138 |
79 |
120 (22.9) |
71 (12.7) |
2.23E-05 |
| >19 |
112 |
66 |
101 (19.2) |
59 (10.6) |
2.61E-04 |
| >20 |
100 |
58 |
92 (17.5) |
53 (9.5) |
5.32E-04 |
|
#Housekeeping genes, *Tissue specific genes. A total of 525 housekeeping and 558 tissue specific genes were analysed. The numbers in parentheses (4th & 5th columns) represent the percentage of genes containing the repeat stretch. §Difference in the distribution of poly (dA.dT) stretches in Hkg and Tsg analysed by applying t-test (for normalizing the difference in sample size). The repeat lengths from >12 to >18 bp are showing very significantly different distributions between Hkg and Tsg. The distributions were examined in 2000 bp upstream region from the gene start site. | |||||
Ganapathi et al. BMC Bioinformatics 2005 6:126 doi:10.1186/1471-2105-6-126 |
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