Table 1

Summary of Medline hit counts for all the full length mRNA genes (16,862 genes) using different search strategies.

Type of primary terma
Positive resultsb
Non reasonable resultsc
Articles per gened

Symbol
10,045
20
198
Expanded
12,028
140
817
Filtered
11,910
22
451

aThe Medline search was conducted using three searching strategies: Symbol refers to a search in which each gene was represented by its official symbol; Expanded refers to searches in which each gene was represented by the gene symbol, all its synonyms and the official gene product name; Filtered refers to searches in which non informative names were filtered out of the expanded list.

bNumber of queries that returned at least one result.

cNumber of queries that returned more than 33,000 results. We used 33,000 as a rough estimate of non reasonable results based on the fact that some of the most investigated genes, like p53, appear in less than 33,000 abstracts.

dThe average number of abstracts per gene counting only genes that appeared at least once and did not appear in more than 33,000 abstracts.

Rubinstein and Simon BMC Bioinformatics 2005 6:12   doi:10.1186/1471-2105-6-12