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List of identified genes. Gene accession numbers, gene descriptions, fold-changes, and p-values for genes identified by the dye-swap method with ANOVA and regularized t-test analysis and the control correction method (CCM). Genes are broadly classified into three groups: proliferation-related, differentiation-related and unclassified. |
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| Proliferation-Related Genes |
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| Classification |
Acc# |
Gene Description |
CCM fold |
CCM p-value |
Dye-Swap fold |
Dye-Swap p-value |
Regularized fold |
Regularized p-value |
|
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| Heat shock proteins |
NM_006597 |
heat shock 70 kDa protein 8 |
-2.8 |
9.5E-6 |
-2.9 |
4.2E-7 |
-2.9 |
8.4E-13 |
| M34664 |
heat shock 60 kDa protein 1 (chaperonin) |
-1.9 |
3.9E-6 |
-1.9 |
4.8E-10 |
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| L15189 |
heat shock 70 kDa protein 9B (mortalin-2) |
-2.2 |
1.4E-3 |
-1.8 |
1.8E-6 |
-1.8 |
6.5E-6 |
|
| M22382 |
Human mitochondrial matrix protein P1 |
-1.8 |
1.5E-5 |
-1.7 |
2.9E-9 |
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| M94859 |
Human calnexin mRNA, complete cds |
-1.8 |
4.1E-3 |
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| L27706 |
Human chaperonin protein (Tcp20) gene complete cds |
-2.1 |
3.8E-4 |
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| Transcription and translation |
D29677 |
helicase with zinc finger domain |
-1.9 |
3.1E-5 |
-1.9 |
2.8E-10 |
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| X91257 |
seryl-tRNA synthetase |
-1.8 |
1.2E-3 |
-1.8 |
4.5E-8 |
-1.9 |
2.0E-11 |
|
| D30655 |
eukaryotic translation initiation factor 4A, isoform 2 |
-1.7 |
5.5E-5 |
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| U76111 |
Human translation repressor NAT1 mRNA, complete cds |
-1.7 |
8.9E-3 |
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| M74719 |
transcription factor 4 |
-1.9 |
2.0E-3 |
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| X13293 |
Human mRNA for B-myb gene |
1.7 |
4.2E-9 |
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| U00968 |
Human SREBP-1 mRNA |
-1.7 |
8.4E-9 |
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| L41490 |
eukaryotic translation elongation factor 1 alpha 1-like 14 |
-1.8 |
1.4E-5 |
-1.7 |
5.3E-5 |
-1.8 |
5.0E-12 |
|
| Fatty acid and sugar metabolism |
D16481 |
Homo sapiens mRNA for mitochondrial 3-ketoacyl-CoA thiolase beta-subunit of trifunctional protein, complete cds |
-1.8 |
5.6E-5 |
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| Y00711 |
Human mRNA for lactate dehydrogenase B (LDH-B) |
-1.8 |
6.9E-5 |
-1.7 |
2.4E-8 |
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| D78130 |
Homo sapiens mRNA for squalene epoxidase, complete cds |
-1.9 |
1.2E-5 |
-1.8 |
9.5E-7 |
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| M37154 |
Human glutamate dehydrogenase (GDH) mRNA, complete cds |
-1.8 |
4.0E-3 |
-1.7 |
8.0E-4 |
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| U62961 |
3-oxoacid CoA transferase |
-2.0 |
1.2E-4 |
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| Y13647 |
Homo sapiens mRNA for stearoyl-CoA desaturase |
-1.9 |
1.5E-6 |
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| GTPase |
Y13286 |
Homo sapiens mRNA for GDP dissociation inhibitor beta |
-1.8 |
1.8E-5 |
-1.7 |
1.3E-6 |
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| X51408 |
Human mRNA for n-chimaerin |
2.1 |
1.8E-2 |
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| Cell cycle |
U47413 |
Human cyclin G1 mRNA, complete cds |
-1.7 |
9.6E-7 |
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| AF139897 |
Homo sapiens BASS1 (BASS1) mRNA, partial cds |
-1.8 |
1.8E-3 |
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| D00265 |
Homo sapiens mRNA for cytochrome c, partial cds |
-2.0 |
2.0E-2 |
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| X68836 |
H. sapiens mRNA for S-adenosylmethionine synthetase |
-2.2 |
8.3E-6 |
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| U19251 |
Homo sapiens neuronal apoptosis inhibitory protein mRNA, complete cds |
1.8 |
1.1E-2 |
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| S45630 |
alpha B-crystallin=Rosenthal fiber component [human, glioma cell line, mRNA, 691 nt] |
2.1 |
2.7E-3 |
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| X86779 |
H. sapiens mRNA for FAST kinase |
1.7 |
1.9E-2 |
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| Oncogenes |
X03541 |
Human mRNA of trk oncogene |
-1.8 |
3.1E-3 |
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| M19722 |
Human fgr proto-oncogene encoded p55-c-fgr protein, complete cds |
-1.9 |
5.0E-3 |
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| X77548 |
H. sapiens cDNA for RFG |
-2.1 |
1.5E-3 |
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| Proliferation |
D63390 |
platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30 kDa |
-1.8 |
4.4E-4 |
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| U62739 |
Human branched-chain amino acid aminotransferase (ECA40) mRNA, complete cds |
1.7 |
1.2E-2 |
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| L12350 |
Human thrombospondin 2 (THBS2) mRNA, complete cds |
1.9 |
2.2E-3 |
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| X06614 |
Human mRNA for receptor of retinoic acid |
1.7 |
2.8E-2 |
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| Y07921 |
Human mRNA for serine protease |
-1.7 |
1.1E-6 |
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| Differentiation-Related Genes |
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| Tumor suppressor |
AF042857 |
Homo sapiens lung cancer antigen NY-LU-12 variant A mRNA, complete cds |
2.1 |
4.4E-3 |
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| Differentiation |
M21300 |
Human small proline rich protein (sprI) mRNA, clone 15B |
1.7 |
2.0E-4 |
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| ECM and vesicle trafficking |
M15395 |
Human leukocyte adhesion protein (LFA-1/Mac-1/p150,95 family) beta subunit mRNA |
2.0 |
2.8E-2 |
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| S72869 |
H4(D10S170) = putative cytoskeletal protein [human, thyroid, mRNA, 3011 nt] |
-1.9 |
3.2E-2 |
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| D21267 |
SNAP25 synaptosomal-associated protein, 25 kDa |
1.9 |
1.7E-2 |
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| U95735 |
Human thrombospondin 2 (THBS2) mRNA, complete cds |
-1.8 |
1.5E-5 |
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| X68194 |
H. sapiens h-Sp1 mRNA |
-1.7 |
4.2E-2 |
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| Z74615 |
collagen, type I, alpha 1 |
2.5 |
5.3E-3 |
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| Immune-response |
U68030 |
chemokine (C-C motif) receptor 6 |
1.8 |
5.8E-3 |
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| X04701 |
Human mRNA for complement component C1r |
-2.4 |
3.3E-2 |
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| DNA repair |
D79983 |
ring finger protein 144 |
1.7 |
2.3E-2 |
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| D29013 |
Homo sapiens mRNA for DNA polymerase beta, complete cds |
1.8 |
7.3E-3 |
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| Unclassified Genes |
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| J02854 |
myosin, light polypeptide 9, regulatory |
2.6 |
4.5E-2 |
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| X58141 |
Human mRNA for erythrocyte adducin alpha subunit |
2.1 |
3.2E-2 |
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| AJ224442 |
Homo sapiens mRNA for putative methyltransferase |
1.8 |
3.4E-3 |
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| X06661 |
Human mRNA for 27-kDa calbindin |
2.1 |
9.0E-3 |
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| U24266 |
aldehyde dehydrogenase 4 family, member A1 |
1.7 |
2.5E-3 |
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| U62432 |
Human nicotinic acetylcholine receptor alpha3 subunit precursor, mRNA, complete cds |
1.8 |
7.0E-3 |
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| U79259 |
Human clone 23945 mRNA, complete cds |
-1.7 |
4.2E-3 |
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| M18533 |
Homo sapiens dystrophin (DMD) mRNA, complete cds |
-2.5 |
1.1E-2 |
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| J05401 |
Human sarcomeric mitochondrial creatine kinase(MtCK) gene, complete cds |
2.2 |
1.5E-2 |
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| D13315 |
Human mRNA for lactoyl glutathione lyase |
-1.7 |
4.6E-7 |
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| AB001740 |
Homo sapiens mRNA for p27 |
1.8 |
8.6E-4 |
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| M15661 |
Human ribosomal protein mRNA |
-1.7 |
1.3E-4 |
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Yao et al. BMC Bioinformatics 2004 5:99 doi:10.1186/1471-2105-5-99 |
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