Table 2

Statistical Details of ROC Curves. Analysis of 100 sequences, 50 with and 50 without, translation initiation sites, for ability to predict presence vs absence of translation inititiation sites (Figures 2 and 3).

A. ROC curve values for each program.


Curve

Area

SE

p

95% CI of Area

ATGpr

0.850

0.0378

<0.0001

0.776 to 0.924

NetStart

0.715

0.0521

<0.0001

0.613 to 0.817

Diogenes

0.706

0.0514

<0.0001

0.605 to 0.806

ESTScan

0.524

0.0580

0.3408

0.410 to 0.638


B. ROC curve values for comparisons between two programs.


Contrast

Difference

p


NetStart v Diogenes

0.009

0.8838

NetStart v ATGpr

-0.136

0.0105

Diogenes v ATGpr

-0.145

0.0072

ESTScan v ATGpr

-0.327

-

NetStart v ESTScan

0.191

-

Diogenes v ESTScan

0.182

-


Nadershahi et al. BMC Bioinformatics 2004 5:14   doi:10.1186/1471-2105-5-14

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