Table 1 |
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The Outlier mRNA Set (Candidate Target List) |
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Transcription factors and other nucleic-acid binding proteins (15) |
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homeo box B8 (HOXB8) |
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E2F transcription factor 6 (E2F6) |
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transcription factor 20 (AR1) (TCF20) |
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DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 (DDX51) |
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similar to ATP-dependent RNA helicase DDX24 (DEAD-box protein 24) (LOC221311) |
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myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 (MLLT1) |
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high mobility group AT-hook 2 (HMGA2) |
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polymerase (DNA directed), theta (POLQ) |
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strand-exchange protein 1 (SEP1) |
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hypothetical protein FLJ12994 – RFX DNA-binding domain |
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similar to LINE-1 reverse transcriptase homolog (LOC285907) |
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similar to hypothetical protein (L1H 3 region) – related to reverse transcriptase |
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similar to putative p150 (LOC282945) – related to reverse transcriptase |
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similar to reverse transcriptase related protein (LOC222252) |
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similar to RTl1 (LOC376283) – related to reverse transcriptase |
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Kinases, receptors and other signaling proteins (13) |
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fyn-related kinase (FRK) |
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WNK kinase, lysine deficient 3 (PRKWNK3) |
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protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (PPP2R5E) |
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EphA5 receptor (EPHA5) |
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killer cell lectin-like receptor subfamily A, member 1 (KLRA1) |
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polycystin and REJ (sperm receptor for egg jelly homolog, sea urchin)-like (PKDREJ) |
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integrin, alpha X (antigen CD11C (p150), alpha polypeptide) (ITGAX) |
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inositol 1,4,5-triphosphate receptor, type 1 (ITPR1) |
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hypothetical protein FLJ32810 – RhoGAP domain, SH3 domain |
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hypothetical protein FLJ00058 – G protein gamma 7 |
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Rho GTPase-activating protein (RICS) |
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hypothetical protein FLJ30899 – probable ras GAP |
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similar to ADP-ribosylation factor-like membrane-associated protein (LOC132946) – ARF-like small GTPase domain, Sar1p-like member of the Ras-family |
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Membrane and extracellular proteins (11) |
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Laminin, beta 4 (LAMB4) |
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laminin, gamma 2 (LAMC2) |
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fibronectin 1 (FN1) |
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collagen, type IV, alpha 5 (Alport syndrome) (COL4A5) |
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collagen, type XIX, alpha 1 (COL19A1) |
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similar to Voltage-dependent anion-selective channel protein 1 (VDAC-1) |
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ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide (ATP1A2) |
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complement component 1, q subcomponent, beta polypeptide (C1QB) |
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hypothetical protein FLJ20506 – transmembrane protein |
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MAM domain containing glycosylphosphatidylinositol anchor 1 (MDGA1) – Ig, MAM domains |
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similar to TCAM-1 (LOC284171) |
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Cytoskeletal domain-containing proteins (7) |
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myosin heavy chain Myr 8 (MYR8) |
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ankyrin repeat domain 17 (ANKRD17) |
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KIAA1817 protein – intermediate filament, ATPase, PDZ, Band 4.1, FERM domains |
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chromosome 10 open reading frame 39 (C10orf39) – homologous to myosin, plectin |
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oxysterol binding protein 2 (OSBP2) – pleckstrin homology domain |
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KIAA1202 protein – PDZ, ATPase domains |
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hypothetical protein FLJ23529 – homolgous to dynein heavy chain |
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Miscellaneous or unknown function (26) |
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cell cycle progression 2 protein (CPR2) |
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olfactomedin 3 (OLFM3) |
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histidine rich calcium binding protein (HRC) |
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interferon-related developmental regulator 1 (IFRD1) |
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KIAA1301 protein – NEDD4-related E3 ubiquitin ligase NEDL2 |
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KIAA1203 protein – ubiquitin C-terminal hydrolase |
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hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) |
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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) |
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KIAA1854 protein – leucine rich repeat C-terminal domains |
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testis specific, 14 (TSGA14) |
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chromosome 4 open reading frame 1 (C4orf1)-membrane AND nuclear protein |
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hypothetical protein FLJ33069 |
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hypothetical protein FLJ38464 |
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hypothetical protein LOC285431 |
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hypothetical protein LOC284107 |
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similar to agCP1362 [Anopheles gambiae str. PEST] (LOC344751) |
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KIAA1632 protein |
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similar to hypothetical protein D11Ertd497e (LOC343360) |
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LOC138724 |
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LOC343460 |
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LOC340963 |
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LOC343220 |
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LOC285842 |
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LOC352767 |
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LOC350293 |
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Smalheiser and Torvik BMC Bioinformatics 2004 5:139 doi:10.1186/1471-2105-5-139 |
