Table 2

List of Normalization Methods

List of normalization methods including print-tip scale normalization

Method
Notation
Description


O
Original data

Global
G
Global median normalization

GP
Global median normalization on each print-tip

GPS
Global median normalization on each print-tip with scale normalization

G.s
Global median normalization and between-slide scale normalization

GP.s
Global median normalization on each print-tip and between-slide scale normalization

GPS.s
Global median normalization on print-tip with scale normalization and between-slide scale normalization

Linear
L
Intensity dependent linear regression normalization

LP
Intensity dependent linear regression normalization on each print-tip

LPS
Intensity dependent linear regression normalization on each print-tip with scale normalization

L.s
Intensity dependent linear regression normalization and between-slide scale normalization

LP.s
Intensity dependent linear regression normalization on each print-tip and between-slide scale normalization

LPS.s
Intensity dependent linear regression normalization on each print-tip with scale normalization and between-slide scale normalization

Nonlinear
N
Intensity dependent nonlinear regression normalization (LOWESS)

NP
Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip

NPS
Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip with scale normalization

N.s
Intensity dependent nonlinear regression normalization (LOWESS) and between-slide scale normalization

NP.s
Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip and between-slide scale normalization

NPS.s
Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip with scale normalization and between-slide scale normalization

Park et al. BMC Bioinformatics 2003 4:33   doi:10.1186/1471-2105-4-33