Table 2

List of Normalization Methods

List of normalization methods including print-tip scale normalization


Method

Notation

Description


O

Original data


Global

G

Global median normalization

GP

Global median normalization on each print-tip

GPS

Global median normalization on each print-tip with scale normalization

G.s

Global median normalization and between-slide scale normalization

GP.s

Global median normalization on each print-tip and between-slide scale normalization

GPS.s

Global median normalization on print-tip with scale normalization and between-slide scale normalization


Linear

L

Intensity dependent linear regression normalization

LP

Intensity dependent linear regression normalization on each print-tip

LPS

Intensity dependent linear regression normalization on each print-tip with scale normalization

L.s

Intensity dependent linear regression normalization and between-slide scale normalization

LP.s

Intensity dependent linear regression normalization on each print-tip and between-slide scale normalization

LPS.s

Intensity dependent linear regression normalization on each print-tip with scale normalization and between-slide scale normalization


Nonlinear

N

Intensity dependent nonlinear regression normalization (LOWESS)

NP

Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip

NPS

Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip with scale normalization

N.s

Intensity dependent nonlinear regression normalization (LOWESS) and between-slide scale normalization

NP.s

Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip and between-slide scale normalization

NPS.s

Intensity dependent nonlinear regression normalization (LOWESS) on each print-tip with scale normalization and between-slide scale normalization


Park et al. BMC Bioinformatics 2003 4:33   doi:10.1186/1471-2105-4-33

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