Table 1

Features evaluated for the design of our method

Abbr.

Feature name


Evolutionary features

C

conservation likelihood

M

mutation likelihood

Pm

mutation site evolutionary profile

Pn

neighbourhood evolutionary profile

Pi

mutation site information content

Pi+

mutation area information contents

S

SIFT score

Mx

PAM evolutionary matrix

Structural features

Ss

secondary structure

As

accessible surface area

D

regions of disorder


Folkman et al. BMC Bioinformatics 2013 14(Suppl 2):S6   doi:10.1186/1471-2105-14-S2-S6

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