Table 8

Comparison of performance based on secondary structure

Secondary Structure

Predictors

Sn

Sp

Acc

MCC


Helix

iStable

0.702

0.933

0.850

0.666

I-Mutant_PDB

0.415

0.901

0.728

0.371

I-Mutant_SEQ

0.520

0.929

0.784

0.509

AUTO-MUTE_RF

0.563

0.987

0.834

0.647

AUTO-MUTE_SVM

0.495

0.957

0.792

0.536

MUPRO_SVM

0.639

0.915

0.818

0.591

PoPMuSiC2.0

0.250

0.957

0.708

0.311

CUPSAT

0.541

0.778

0.693

0.323

Sheet

iStable

0.691

0.946

0.876

0.676

I-Mutant_PDB

0.348

0.944

0.782

0.385

I-Mutant_SEQ

0.495

0.948

0.825

0.520

AUTO-MUTE_RF

0.455

0.984

0.838

0.567

AUTO-MUTE_SVM

0.297

0.996

0.805

0.426

MUPRO_SVM

0.417

0.904

0.770

0.370

PoPMuSiC2.0

0.310

0.956

0.776

0.363

CUPSAT

0.417

0.796

0.697

0.213

Other

iStable

0.680

0.943

0.847

0.666

I-Mutant_PDB

0.365

0.893

0.699

0.311

I-Mutant_SEQ

0.358

0.924

0.716

0.354

AUTO-MUTE_RF

0.479

0.995

0.805

0.595

AUTO-MUTE_SVM

0.386

0.954

0.745

0.434

MUPRO_SVM

0.485

0.900

0.748

0.433

PoPMuSiC2.0

0.330

0.889

0.688

0.270

CUPSAT

0.474

0.766

0.662

0.249


Helix: α helix; Sheet: β sheet; Other: turns and coil.

Chen et al. BMC Bioinformatics 2013 14(Suppl 2):S5   doi:10.1186/1471-2105-14-S2-S5

Open Data