Table 2

Comparison of prediction result with M1311

Predictors

Sn

Sp

Acc

MCC


iStable

0.944

0.981

0.969

0.930

I-Mutant_PDB

0.555

0.922

0.800

0.530

I-Mutant_SEQ

0.702

0.973

0.883

0.734

AUTO-MUTE_RF

0.893

0.991

0.958

0.906

AUTO-MUTE_SVM

0.772

0.975

0.907

0.789

MUPRO_SVM

0.775

0.956

0.896

0.761

PoPMuSiC2.0

0.313

0.941

0.724

0.341

CUPSAT

0.579

0.823

0.742

0.411

Majority Voting

0.737

0.984

0.902

0.779


I-Mutant_PDB: I-Mutant2.0 prediction strategy using PDB ID.

I-Mutant_SEQ: I-Mutant2.0 prediction strategy using protein sequence.

AUTO-MUTE_RF: AUTO-MUTE Random Forest prediction model.

AUTO-MUTE_SVM: AUTO-MUTE SVM prediction model.

MUPRO_ SVM: MUPRO SVM prediction model.

Chen et al. BMC Bioinformatics 2013 14(Suppl 2):S5   doi:10.1186/1471-2105-14-S2-S5

Open Data