Table 10

Evaluation of iStable prediction results with data from different protein superfamilies

Protein categories

Predictors

Sn

Sp

Acc

MCC


Nucleic acid binding

iStable

0.550

0.943

0.795

0.567

I-Mutant_PDB

0.550

0.852

0.742

0.439

I-Mutant_SEQ

0.300

0.943

0.704

0.343

AUTO-MUTE_RF

0.250

0.971

0.704

0.359

AUTO-MUTE_SVM

0.250

0.943

0.684

0.262

MUPRO_SVM

0.450

0.857

0.704

0.395

PoPMuSiC2.0

0.400

0.910

0.724

0.355

CUPSAT

0.350

0.552

0.476

-0.073

Enzyme

iStable

0.451

0.797

0.720

0.334

I-Mutant_PDB

0.253

0.869

0.756

0.135

I-Mutant_SEQ

0.242

0.878

0.762

0.131

AUTO-MUTE_RF

0.138

0.978

0.825

0.217

AUTO-MUTE_SVM

0.057

0.965

0.800

0.049

MUPRO_SVM

0.281

0.859

0.753

0.144

PoPMuSiC2.0

0.344

0.931

0.824

0.328

CUPSAT

0.390

0.740

0.676

0.112

Protein-protein interaction related

iStable

0.357

0.943

0.831

0.379

I-Mutant_PDB

0.207

0.858

0.733

0.088

I-Mutant_SEQ

0.361

0.798

0.714

0.161

AUTO-MUTE_RF

0.129

0.965

0.805

0.145

AUTO-MUTE_SVM

0.079

0.970

0.799

0.100

MUPRO_SVM

0.204

0.864

0.737

0.076

PoPMuSiC2.0

0.100

0.964

0.798

0.091

CUPSAT

0.461

0.778

0.717

0.216


Chen et al. BMC Bioinformatics 2013 14(Suppl 2):S5   doi:10.1186/1471-2105-14-S2-S5

Open Data