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This article is part of the supplement: Selected articles from the Eleventh Asia Pacific Bioinformatics Conference (APBC 2013): Bioinformatics

Open Access Proceedings

iStable: off-the-shelf predictor integration for predicting protein stability changes

Chi-Wei Chen1, Jerome Lin1 and Yen-Wei Chu12345*

Author Affiliations

1 Institute of Genomics and Bioinformatics, National Chung Hsing University 250, Kuo Kuang Rd., Taichung 402, Taiwan

2 Biotechnology Center, National Chung Hsing University 250, Kuo Kuang Rd., Taichung 402, Taiwan

3 Agricultural Biotechnology Center, National Chung Hsing University 250, Kuo Kuang Rd., Taichung 402, Taiwan

4 Institute of Molecular Biology, National Chung Hsing University 250, Kuo Kuang Rd., Taichung 402, Taiwan

5 Graduate Institute of Biotechnology, National Chung Hsing University 250, Kuo Kuang Rd., Taichung 402, Taiwan

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BMC Bioinformatics 2013, 14(Suppl 2):S5  doi:10.1186/1471-2105-14-S2-S5

Published: 21 January 2013

Additional files

Additional file 1:

M3131_Decreased and M3131_Increased show the integrated training data M3131 separated into positive (increasing stability) dataset and negative (decreasing stability) dataset. iStable_Comparison_results presents the different results of training conditions and comparisons of different predictors.

Format: ZIP Size: 115KB Download file

Open Data

Additional file 2:

Superfamily_M1311 and Superfamily_M1820 record the superfamilies refer to the PDB IDs in M1311and M1820datasets. SF_DNA BINDING, SF_Enzyme, and SF_Protein-protein-interaction list the PDB IDs belong to three major categories.

Format: ZIP Size: 4KB Download file

Open Data