Table 2

2009-H1N1 HA epitope interacting residues with DM1-TCR and HLA-B*4405 complexes.

Position

Epitope sequence

HLA/epitope (solvent-exposed residues)

TCR-HLA/epitope (interacting residues)


50

LEDKHNGKL

Lys4

Lys4

128

FERFEIFPK

Arg3, Glu5

Arg3

188

KEVLVLWGI

-

Lys1, Leu4, Leu6, Gly8

251

VEPGDKITF

Asp5, Lys6

Asp5, Lys6

412

KEFNHLEKR

Asn4, His5, Glu7

Glu2, Asn4, His5, Glu7

446

LENERTLDY

-

Leu1, Glu4, Asp8

463

YEKVRSQLK

Arg5

Arg5, Lys9

493

MESVKNGTY

Met1

Met1, Lys5

514

REEIDGVKL

Lys8

Lys8

131

FEIFPKTSS

Phe1

Phe1, Lys6

229

PEIAIRPKV

Ala4, Ile5

Ile5

400

IEKMNTQFT

Lys3, Met4

Glu2, Lys3, Met4, Asn5, Thr6

421

IENLNKKVD

-

Lys7, Asp9

475

KEIGNGCFE

-

Lys1, Glu2

482

FEFYHKCDN

-

Lys6

240

QEGRMNYYW

-

Asn6, Tyr7, Tyr8, Trp9

259

FEATGNLVV

Thr4, Gly5, Asn6

Glu2, Thr4, Gly5


Su et al. BMC Bioinformatics 2013 14(Suppl 2):S21   doi:10.1186/1471-2105-14-S2-S21

Open Data