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This article is part of the supplement: Selected articles from the Eleventh Asia Pacific Bioinformatics Conference (APBC 2013): Bioinformatics

Open Access Proceedings

Molecular docking analysis of 2009-H1N1 and 2004-H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development

Chinh TT Su1, Christian Schönbach34* and Chee-Keong Kwoh12*

Author Affiliations

1 Bioinformatics Research Centre, School of Computer Engineering, Nanyang Technological University, Singapore 639798

2 Biomedical Engineering Research Centre, College of Engineering, Nanyang Technological University, Singapore 637553

3 Department of Bioscience and Bioinformatics, School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan

4 Biomedical Informatics Research Center, Kyushu Institute of Technology, Fukuoka 820-8502, Japan

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BMC Bioinformatics 2013, 14(Suppl 2):S21  doi:10.1186/1471-2105-14-S2-S21

Published: 21 January 2013

Additional files

Additional file 1:

MAFFT multiple sequence alignment of pandemic strains (2009 - the top 7 sequences) HA proteins to HA (1918 - South Carolina) and WHO vaccine HA (the last 3 sequences).

Format: PDF Size: 494KB Download file

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Open Data

Additional file 2:

Predicted HA T cell epitopes of H1N1 2009 strains compared to 1918 and WHO-1999-2006-2007 strains.

Format: XLS Size: 39KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Physicochemical properties of NetCTL-predicted HLA-B44 restricted T cell epitope candidates (A) and non-epitopes (B).

Format: PDF Size: 93KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 4:

Residues of domain α1, α2 of HLA-B*4405 interacting with DM1-TCR.

Format: PDF Size: 67KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data