Table 2

Results for knockout strains derived by MOMAKnock on the core E. coli metabolic network

MOMAKnock

MOMA Flux


K

Knockouts

Succi

Biomass

Succi

Biomass

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2

6pg→ ru5p+co2+nadph, suc→ fum + fadh2 (or fadh2 + 0.5o2→2atp)

54.41

13.44

40.25

12.65

124.86

3

6pg→ru5p+co2+nadph, fadh2+0.5o2 → 2atp (or suc→ fum + fadh2), ser→ gly + meethf

54.98

12.08

45.71

11.80

157.67

4

pep→ pyr + atp, g6p→ 6pg+nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2)

57.75

11.24

52.73

10.76

318.52

5

pep → pyr + atp, g6p → 6pg + nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2+0.5o2→2atp (or suc→ fum + fadh2), nadh → nadph

65.25

7.90

53.31

7.65

352.26


Ren et al. BMC Bioinformatics 2013 14(Suppl 2):S17   doi:10.1186/1471-2105-14-S2-S17

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