Table 1

Results for knockout strains derived by OptKnock on the core E. coli metabolic network

OptKnock

MOMA Flux


K

Knockouts

Succi

Biomass

Succi

Biomass

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2

kdpg→ pyr + gap (or 6pg→kdpg), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2)

102.98

14.36

26.32

13.18

398.75

3

g6p → 6pg + nadph, 3pg+glu→ser+akg+nadh, nadh → nadph

121.02

7.06

24.45

5.23

633.25

4

g6p → 6pg + nadph, dhap → gap, fadh2 + 0.5o2→2atp (or suc→fum + fadh2), glyc → glyc(ext)

118.71

5.00

84.56

5.00

482.70

5

pep → pyr + atp, mal→ pyr+co2 + nadph, dhap + nadh → glyc3p, glyc3p → glyc, fadh2 + 0.5o2→2atp (or suc→fum + fadh2)

126.33

10.91

38.73

12.75

518.65


Ren et al. BMC Bioinformatics 2013 14(Suppl 2):S17   doi:10.1186/1471-2105-14-S2-S17

Open Data