Table 3

Comparison among the proposed approach and some of the other approaches.

Methods

Protein complexes

Protein fraction

p-Value


G2/M transition of mitotic cell cycle


Proposed System

app1, swe1, hsl7

2/3

2.17e-03

PINCoC

swe1, hsl7

2/2

6.90e-04

UVCluster

app1, swe1, hsl7

2/3

2.17e-03


Actin Filament Depolymerization


Proposed System

act1, srv2, bnr1, bni1, cof1, trm5, aip1

4/7

4.92e-10

PINCoC

bnr1, bni1, pfy1, act1, srv2, aip1, trm5

5/7

1.52e-07

UVCluster

act1, srv2, aip1, trm5, cof1

4/5

7.30e-04


Actin Cytoskeleton Organization


Proposed System

sla2, abp1, yor284w, rvs167, ysc84, sla1, ynl086w, ypl246c, rvs161, acf2, ybr108w, yjr083c, ygr268c, ypr171w, yhr133c

7/15

4.65e-08

PINCoC

sla2, abp1, yor284w, rvs167, ysc84, app1, rvs161, ynl086w, yjr083c, acf2

6/10

6.72e-08

UVCluster

sla2, abp1, yor284w, rvs167, ysc84, sla1, ygr268c

4/7

5.93e-05


Actin Polymerization or Depolymerization


Proposed System

crn1, svl3

0/2

> 0.01

PINCoC

crn1, svl3, las17, yhr133c, cof1

3/5

9.07e-06

UVCluster

crn1, svl3

0/2

> 0.01


Rho Protein Signal Trasduction


Proposed System

----

---

---

PINCoC

cdc42, cla4, gic2

3/3

1.76e-06

UVCluster

cdc42, cla4, gic2

3/3

1.76e-06


The table reports a comparison among the proposed approach and two different approaches, called respectively PINCoC and UVCluster, that have been previously tested with this database. Proposed system outperforms result of the other tools with respect to the complexes Actin Filament Depolymerization and Actin Cytoskeleton Organization.

Fiannaca et al. BMC Bioinformatics 2013 14(Suppl 1):S5   doi:10.1186/1471-2105-14-S1-S5

Open Data