Visualization of gene structures on protein structures. In this figure, intron positions and phases are visualized in a protein structure. The gene structure of human HsCoro1A (see Figure 1) was mapped onto the Coro1A structure from mouse . The two different output formats are shown for comparison. A) Illustrates colouring of exons mapped to the protein structure (color_exons.py). For better orientation, the N- and C-termini and the positions of the last residues in each putative exon are given. The number in brackets denotes an intron position covered by another structural element. C) Displays the phases of the introns (color_splicesites.py). Numbers indicate the respective intron phases. In both figures, introns occurring in any of the sequences within the MSA are shown (-consensus 0). Contrary, introns conserved in 80% of all proteins (default value) are shown in B) and D). Analogous to A) and C), B) refers to color_exons.py and D) to color_splicesites.py.
Hammesfahr et al. BMC Bioinformatics 2013 14:77 doi:10.1186/1471-2105-14-77