Selection of estimated coverage functions for simulation conditions with 50,000 reads. The three fragment size distributions depicted in Figure 2 were used to simulate the data, where the coverage function implied by these three distributions is represented by the solid lines. The dashed lines indicate the mean of the estimated across all 10,000 simulations. The dotted line is an example of an estimated coverage function that has mean error identical to the 99th percentile of the 10,000 estimates.
van den Oord et al. BMC Bioinformatics 2013 14:50 doi:10.1186/1471-2105-14-50