Simulation time for a continuous model. x-axis: number of involved nodes. y-axis: Time (in seconds) to simulate a standardized network with the given number of nodes. Note that in all figures the number of nodes refers to the number of actual network nodes xi as opposed to the number of nodes in the Boolean tree. To highlight the time complexity of the different calculation methods, the data series are scaled to coincide for a network with 4 nodes. Actual simulation times for 4 nodes: Jimena (red) = 0.019 s, Odefy (blue) = 0.040 s, Squad (green) = 0.046 s. The Additional file 1 explains the definition of the network for a given number of nodes.
Karl and Dandekar BMC Bioinformatics 2013 14:306 doi:10.1186/1471-2105-14-306