Table 3

Comparison of different methods for classifying exposed/buried residues on 392 interface TM residues of the independent test set by rASA derived from both subunit structure and complete structure (in parentheses)
Measurements TMexpo MPRAP TMX Rhythm (membrane-coil) Rhythm (channel)
MCC 0.14 (0.22) 0.12 (0.25) 0.13 (0.17) 0.08 (−0.06) 0.19 (0.28)
Sensitivity 73.11% (81.25%) 56.29% (67.23%) 66.17% (72.78%) 67.72% (63.22%) 66.10% (77.97%)
Specificity 48.57% (38.50%) 64.71% (57.59%) 55.88% (43.98%) 45.00% (30.77%) 64.29% (49.32%)
Precision 93.55% (55.91%) 94.00% (59.50%) 93.70% (55.04%) 90.68% (46.61%) 93.98% (55.42%)
Accuracy 70.92% (59.44%) 57.07% (62.23%) 65.23% (57.95%) 65.17% (46.63%) 65.91% (62.12%)

Lai et al.

Lai et al. BMC Bioinformatics 2013 14:304   doi:10.1186/1471-2105-14-304

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