Reliability weight of the edge e1 using AdjstCD depends on the outgoing edges e6,e7, …,e10. However, in a case of noisy network there is a possibility that many of these outgoing edges may not be reliable. Therefore, the reliability of the edge e1 should not be influenced by all of the outgoing edges.
Zaki et al. BMC Bioinformatics 2013 14:163 doi:10.1186/1471-2105-14-163