Table 2

Performance on I-TASSER decoys
Energy/Program Method Criterion-1 (%) Criterion-2 (/40) ± Std Dev.
I-TASSER Energy only 59.7 NA (baseline)
with HS-Forest 68.4 27.2 ± 1.9
GaFolder Energy only 57.1 19
with HS-Forest 75.3 27.3 ± 1.8
Consensus Energy only 67.4 22
with HS-Forest 72.1 26.5 ± 1.2
Durandal 72.0 25.7 ± 1.2
Calibur-lite 74.1 26.5 ± 0.5
SPICKER 2.0 72.6 25.0

Criterion-1 measures the percentage of decoys that the top scoring decoy outperformed; Criterion-2 measures the frequency with which the top decoy selected by a given method has a lower Cα RMSD than the one selected based on energy alone. The values behind ± are the standard deviations among different runs.

Zhou and Wishart

Zhou and Wishart BMC Bioinformatics 2013 14:11   doi:10.1186/1471-2105-14-11

Open Data