Table 1

Performance on Rosetta decoys
Energy/Program Method Criterion-1 (%) Criterion-2 (/35) ± Std Dev.
Rosetta Energy only 80.0 NA (baseline)
with HS-Forest 85.2 24.7 ± 1.8
GaFolder Energy only 71.8 15.0
with HS-Forest 80.4 20.0 ± 1.2
Consensus Energy only 81.2 17.0
with HS-Forest 83.3 18.0 ± 0.7
Durandal 82.5 16.0 ± 1.8
Calibur-lite 78.9 13.6 ± 0.7
Rosetta Clustering 80.0 20

Criterion-1 and Criterion-2 are defined in the manuscript. Criterion-1 measures the percentage of decoys that the top-scoring decoy outperformed; Criterion-2 measures the frequency with which the top decoy, selected by a given method, has a lower Cα RMSD than the one selected by the energy alone. The values behind ± are the standard deviations among different runs.

Zhou and Wishart

Zhou and Wishart BMC Bioinformatics 2013 14:11   doi:10.1186/1471-2105-14-11

Open Data