Table 2

Details of predicted protein interactions in M. tuberculosis

Species

Database

Original PPI

Predicted PPI

Percentage (%)


By machine learning


E. coli

ECID

14,058(positive)+

27,882(negative)

12,899

27.97


By interolog


Escherichia coli

IntAct

14,158

16,468

35.71

Campylobacter jejuni

IntAct

11,870

7,674

16.64

Treponema pallidum

IntAct

3,744

324

0.70

Synechocystis

IntAct

2,625

2,481

5.38

Myxococcus xanthus

IntAct

384

253

0.55

Synechocystis sp.

IntAct

219

220

0.48

Rickettsia sibirica

IntAct

282

24

0.05

Streptococcus pneumoniae

IntAct

193

47

0.10

Drosophila melanogaster

DIP

22,650

1,558

3.38

Saccharomyces cerevisiae

DIP

21,769

2,701

5.86

Caenorhabditis elegans

DIP

3,979

229

0.50

Homo sapiens

DIP

1,485

84

0.18

Mus musculus

DIP

287

36

0.06

Rattus norvegicus

DIP

69

2

0.15


Total: 46,119 interactions in 3,465 proteins (with 530 known PPIs)


Liu et al. BMC Bioinformatics 2012 13(Suppl 7):S6   doi:10.1186/1471-2105-13-S7-S6

Open Data