Table 2

Species and parameters included in the mathematical model.

Parameter or species

Description

Value

Units


X

LuxR protein concentration per cell

Variable

AU cell-1

A

LuxR-HSL activated complex concentration per cell

Variable

AU cell-1

R

RFP per cell

Variable

AU cell-1

H

Inducer concentration

Known input

nM

n

DNA copy number

Estimated

-

αtet

LuxR synthesis rate per cell per DNA copy

2.3(a)

AU min-1 cell-1

αlux

Maximum RFP synthesis rate per cell per DNA copy

Estimated

AU min-1 cell-1

γX

LuxR protein degradation rate

6*10-2

min-1

μ

Cell growth rate

Estimated

min-1

KH

Dissociation constant of HSL-LuxR

553

nM

KA

Dissociation constant of HSL-LuxR complex and luxI promoter

Estimated

AU cell-1

nH

Hill cooperativity constant of HSL-LuxR

2

-

nA

Hill cooperativity constant of HSL-LuxR complex and luxI promoter

Estimated

-


(a) From unpublished data of our lab.

Parameter values that have not been estimated in this study are described in [48]. AU indicates arbitrary units of RFP.

Zucca et al. BMC Bioinformatics 2012 13(Suppl 4):S11   doi:10.1186/1471-2105-13-S4-S11

Open Data