Figure 12.

Specificity of the proposed model with reduced versus expanded scope of biological replication. Specificity of the proposed model with reduced versus expanded scope of biological replication in the study of breast cancer cell lines. Results from comparing protein abundances between two artificial groups of replicates within (a) the low invasive cell line under normoxia and (b) the high invasive cell line under normoxia. X-axis: p-values adjusted to control for the FDR using the approach by Benjamini and Hochberg. Y-axis: number of significant proteins. Solid black line: reduced scope of biological replication. Dashed red line: expanded scope of biological replication.

Clough et al. BMC Bioinformatics 2012 13(Suppl 16):S6   doi:10.1186/1471-2105-13-S16-S6