Figure 11.

Sensitivity of the proposed model with reduced versus expanded scope of biological replication. Sensitivity of the proposed model with reduced versus expanded scope of biological replication for comparing protein abundances between conditions as described at the beginning of Section 3. (a) Study of breast cancer cell lines. (b) Study of subjects with osteosarcoma. X-axis: p-values adjusted to control for the FDR using the approach by Benjamini and Hochberg. Y-axis: number of significant proteins. Solid black line: reduced scope of biological replication. Dashed red line: expanded scope of biological replication.

Clough et al. BMC Bioinformatics 2012 13(Suppl 16):S6   doi:10.1186/1471-2105-13-S16-S6