Table 1

Metrics used for dissimilarity measurements

Dissimilarity Measure

Definitiona


Soergel

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Dice

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Manhattan

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Rogers-Tanimoto

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a Let P1 and P2 be two pharmacophore fingerprints, a be the count of bits which are set to 1 in both P1 and P2, b be the count of bits which are set to 1 in P1 but not in P2, c be the count of bits which are set to 1 in P2 but not in P1, and d be the count of bits which are set to 0 in both P1 and P2. So a is called the number of total matches, b and c are called the number of single matches, and d is called the number of no matches.

Fu et al. BMC Bioinformatics 2012 13(Suppl 15):S3   doi:10.1186/1471-2105-13-S15-S3

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