Figure 2.

Overview of the MILES approach. (1) Structure preprocessing and conformational sampling. (2) Creating pharmacophore fingerprints and significance analysis of pharmacophore models. (3) Instance-based feature mapping based on structural similarity measures. (4) Joint feature selection and classification using 1-norm SVM.

Fu et al. BMC Bioinformatics 2012 13(Suppl 15):S3   doi:10.1186/1471-2105-13-S15-S3