Minimum spanning tree of single-clone sample S6. Each node is a unique haplotype. The diameter of the node is proportional to the square root of its frequency. The true haplotype is shown in red, haplotypes with indel errors only are shown in yellow, haplotypes with nucleotide substitutions only are shown in blue and haplotypes with both types of errors are shown in green.
Skums et al. BMC Bioinformatics 2012 13(Suppl 10):S6 doi:10.1186/1471-2105-13-S10-S6