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DNA methylation arrays as surrogate measures of cell mixture distribution

Eugene A Houseman1*, William P Accomando2, Devin C Koestler3, Brock C Christensen3, Carmen J Marsit3, Heather H Nelson4, John K Wiencke5 and Karl T Kelsey2,6

1 College of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA

2 Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA

3 Section of Biostatistics and Epidemiology, Dartmouth Medical School, Hanover, NH 03755, USA

4 Department of Epidemiology, University of Minnesota, Minneapolis, MN 55455, USA

5 Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94158, USA

6 Department of Epidemiology, Brown University, Providence, RI 02912, USA

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BMC Bioinformatics 2012, 13:86 doi:10.1186/1471-2105-13-86

Published: 8 May 2012

Additional files

Additional file 1:

Houseman-WBC-BMCBioinformatics- Supplement.pdf. Additional theoretical details, simulation descriptions and results, and additional figures and result tables [43-52].

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Additional file 2:

Houseman-WBC-BMCBioinformatics-Software-v2. Sample R software (compressed).

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