Each panel depicts the relation between the matched gene expression and DNA copy number data (as produced by one of the matching procedure) for the A_23_P168211 probe from the TCGA data set (with Agilent expression arrays). The red line is the best fitting piece-wise linear spline (as obtained from the method described in ). The pink area represent the 95% confidence intervals for the fitted relationship. The vertical dashed lines separate the samples with a normal from those with a gain, and those with a gain from those with an amplification.
van Wieringen et al. BMC Bioinformatics 2012 13:80 doi:10.1186/1471-2105-13-80