Table 2

Results from tests of the atomic predictor on finding the binding location of calcium ions
PDB Code 1ANX 1AYP 1CGV 1CLM 1OMD 3CLN 1SAC 2SCP 3ICB 3PAL 5CPV
ROC Area 0.92 0.57 1.00 0.94 0.95 0.97 0.96 0.97 0.96 0.98 0.97

Shown are the 11 proteins used as test cases by Altman et. al [45]. To test these, we first trained a predictor on 100 examples of calcium binding, then evaluated each of the above protein surfaces using this predictor to generate an ROC curve for each test. The number below each PDB code is the area under its respective ROC curve. 1.0 indicates a perfect score, with all true positives found and no false positives. See Figure 1 for illustrations to help interpret these numbers.

Cipriano et al.

Cipriano et al. BMC Bioinformatics 2012 13:314   doi:10.1186/1471-2105-13-314

Open Data