(Evaluation of the robustness of HIDEN) The Z-score of HIDEN’s hierarchical decomposition of the S. cerevisiae, E. coli and H. sapiens network using adjacency and reachability penalties. Level assignment is done on the original network. The Z-score is computed on the mutant network where the network is mutated at increasing mutation percentages. The results are reported for three different highest allowed levels, namely three, six and eight.
Gülsoy et al. BMC Bioinformatics 2012 13:250 doi:10.1186/1471-2105-13-250