Table 2

Selected statistics on regulation data content for several organisms
E. coli K-12 B. subtilis S. oneidensis Shewanella sp. Synechococcus
MG1655 subtilis168 MR1 W3-18-1 sp. PCC7002
Transcriptional regulation 3118 781 589 569 114
Transcription factor binding 3032 747 589 569 114
Allosteric regulation of RNA-polymerase 66 0 0 0 0
Attenuation 20 34 0 0 0
Translational regulation 97 5 0 0 4
Protein-mediated 31 2 0 0 0
RNA-mediated 59 1 0 0 0
Small-molecule-mediated 5 2 0 0 4
Enzyme modulation 2508 9 0 0 5
Physiologically relevant 210 2 0 0 2
Genes with ≥ 1 transcriptional/translational regulator 1771 1087 542 539 124
Percent of genome 39% 25% 12% 13% 4%
Transcriptional or translational regulators 260 151 62 54 19
Proteins 225 128 62 54 16
RNAs 27 15 0 0 0
Small molecules 8 8 0 0 3
Enzymes subject to modulation 597 8 0 0 3
Physiologically relevanta 114 1 1
Enzyme modulators 1016 6 0 0 5
Physiologically relevanta 108 2 2

aFor enzyme modulation, a distinction is made between physiologically relevant effects and those that have been observed purely in vitro.

Paley et al.

Paley et al. BMC Bioinformatics 2012 13:243   doi:10.1186/1471-2105-13-243

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