Power and false discovery rate (FDR) according to actual depth and minimum allele frequency when using N = 20,50 and 100 chromosomes (from top to bottom) obtained with different methods (legend on upper-right panel). Average depth was 20X. Left column panels show power as a function of actual depth, middle column is the false discovery rate as a function of actual depth, and right column, power as a function of true minor allele frequency (MAF). Average of 100 replicates.
Raineri et al. BMC Bioinformatics 2012 13:239 doi:10.1186/1471-2105-13-239