The mapability of simulated sequences from theE. coli,A. thaliana, and human genomes. Mapping accuracy is shown on a Phred scale ( ) for all three plots. Reads were simulated with base accuracies 1−ρ = 80%, 85%, … , 100%. In the fraction ρof positions that are erroneous, we simulated 10% substitutions, 62% insertions, and 28% deletions. Missing values have no mismapped reads.
Chaisson and Tesler BMC Bioinformatics 2012 13:238 doi:10.1186/1471-2105-13-238