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Open Access Highly Accessed Methodology article

Mapping single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory

Mark J Chaisson1 and Glenn Tesler2*

Author Affiliations

1 Department Secondary Analysis, Pacific Biosciences, 1005 Hamilton Rd, CA, Menlo Park, USA

2 Department of Mathematics, University of California, San Diego, 9500 Gilman Dr, CA, La Jolla, USA

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BMC Bioinformatics 2012, 13:238  doi:10.1186/1471-2105-13-238

Published: 19 September 2012

Additional files

Additional file 1:

Supplementary Text S1. The supplementary text contains additional implementation details for the anchor similarity method, and description of the empirical model based read simulator.

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Additional file 2:

Supplementary Table S1. Supplementary Table S1 gives the command line parameters used to run the benchmarks.

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