Methodology article
Network enrichment analysis: extension of gene-set enrichment analysis to gene networks
1 School of Biotechnology, Royal Institute of Technology, Stockholm, Sweden
2 , Science for Life Laboratory, Stockholm, Sweden
3 Department of Statistics, Inha University, Incheon, South Korea
4 Clinical Proteomics Mass Spectrometry, Karolinska Institutet, Stockholm, Sweden
5 Functional Genomics, Institut Gustave Roussy, Villejuif, France
6 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
BMC Bioinformatics 2012, 13:226 doi:10.1186/1471-2105-13-226
Published: 11 September 2012Additional files
Additional file 1:
Has three sections. Section A has two figures: In Figure S1, we compared z-scores from GEA to those from MNEA and FNEA. In Figure S2, we compared the NEA scores of individual AGSs versus 264 FGSs for the two omics data. Section B contains the list of pathways used in our lung cancer study. Their meanings and references are also given. For pedagogic purposes, in Section C, we provide a fully worked-out example of analysis of lung cancer data from Bild et al.’s.
Format: DOC Size: 238KB Download file
This file can be viewed with: Microsoft Word Viewer
