The InteractomeBrowser plugin. (A) A global and zoom-in view of InteractomeBrowser cell-compartment based layout. Zoom-in view shows some sub-cellular compartments together with node corresponding to gene products. Note that node corresponding to Esr1 appears as green, indicating that regulatory information is available for this gene. (B) Positive interactions (i.e.; activations) appear as green edges with normal arrowheads (here Notch1 is the source). (C) Negative interactions (i.e; repressions) appear as red edges with T-shaped arrowheads (here Mirn17 is the source). (D) Ambiguous interactions (whose repressive or activating status is unknown) appear as violet arrows with dot arrowheads (here with Mycn as source).
Lepoivre et al. BMC Bioinformatics 2012 13:19 doi:10.1186/1471-2105-13-19