Improvement in normalized N50 size after assembly. For each of our 369 bacterial genomes, we plot the initial normalized N50 size (x axis) relative to the normalized N50 size after assembly (y axis) when provided a simulated optical map with the medium error rate, as described in the Methods section. The N50 sizes are normalized by dividing by the genome length. Most genomes exhibit substantial improvement in the normalized N50 size with the exception of complex genomes (with low initial normalized N50 size), and some simple genomes (with initial N50 size already close to the entire genome size).
Lin et al. BMC Bioinformatics 2012 13:189 doi:10.1186/1471-2105-13-189